venofer dosing calculator venofer dosing calculator

Read our. By using this form you agree with the storage and handling of your data by this website. By clicking send, you acknowledge that you have permission to email the recipient with this information. Do not administer Venofer to patients with iron overload. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Applies only to oral form of both agents. an automated flowchart approach. Applies only to oral form of both agents. 2015: 763576. iron sucrose decreases levels of ibandronate by inhibition of GI absorption. The two formulas used are presented below: Iron deficit in mg = Weight in kg x (14 Hb in g/dL) x 2.145, Volume of product required in mL = Iron deficit in mg / C in mg/mL. Ferrlecit has been administered at sequential dialysis sessions by infusion or by slow intravenous injection during the dialysis session itself. Iron deficiency anemia calculator (diagnosis), Iron deficiency anemia vs. Step 2: Calculation and administration of the maximum individual iron dose(s): . Equations used: 1] Calculation of the Total Iron Deficit: Total iron deficit [mg] = body weight [kg] x (target Hb-actual Hb) [g/dl] x 2.4 + depot iron [mg]. Avoid or Use Alternate Drug. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Hemoglobin iron deficit = 60 x (14 - 8) x (2.145) = 772 mg iron. Applies only to oral form of both agents. Monitor Closely (1)cimetidine will decrease the level or effect of iron sucrose by increasing gastric pH. Monitor Closely (1)iron sucrose decreases levels of penicillamine by inhibition of GI absorption. Properly discard this product when it is expired or no longer needed. Applies only to oral form of both agents. Sodium ferric gluconate (Ferrlecit) 62.5 mg . J Med. Applies to didanosine chewable tablets and powder for oral solution; administer 2 hr before or several hours after didanosine oral solution or chewable tablet administration. Situation Analysis Market Size MAT Sales Cr LC MAT Share % MAT Gr % Total Pharma Market 9388.69 100 13.5 Iron Sucrose 11.18 93.81 37.65 Brand Company Saline MAT . Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Applies only to oral form of both agents. Creating an account is free and takes less than 1 minute. 4)Pasricha SR, Flecknoe-Brown SC, Allen KJ, Gibson PR, McMahon LP, Olynyk JK, Roger SD, Savoia HF, Tampi R, Thomson AR, Wood EM, Robinson KL. US residents can call their local poison control center at 1-800-222-1222. iron sucrose decreases levels of liothyronine by inhibition of GI absorption. Minor (1)iron sucrose, captopril. Hemodialysis-dependent CKD: 100 mg elemental iron IV (injection or infusion over 2-5 min) per dialysis session not to exceed total cumulative dose of 1000 mg divided in 3 doses/week. Serious - Use Alternative (1)iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. Applies only to oral form of both agents. Feraheme does not contain antimicrobial preservatives. In case a pediatric patient with a weight below 35 kg is assessed, iron stores are calculated as 15 mg iron for each kg. Most Minor (1)gymnema decreases levels of iron sucrose by inhibition of GI absorption. 2) Koch TA, Myers J, Goodnough LT. (2015) Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Separate dosing of tetracyclines from these products. 1996 Aug;11(4):139-46. We'll do this entirely for free, as long as the calculator has applications for women's health. Applies only to oral form of both agents. On the other hand, slow decreases, such as that in chronic occult gastrointestinal bleeding are often difficult to diagnose. Max Dose. deferasirox decreases levels of iron sucrose by inhibition of GI absorption. 2 DOSAGE & ADMINISTRATION Venofer must only be administered intravenously either by slow injection or by infusion. Applies only to oral form of both agents. vonoprazan will decrease the level or effect of iron sucrose by inhibition of GI absorption. Learn how to store and discard medical supplies safely. Only administer Venofer when personnel and therapies are immediately available for the treatment of serious hypersensitivity reactions. Administer Venofer only intravenously by slow injection or by infusion. Applies only to oral form of both agents. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. David McAuley, Pharm.D. HOW TO USE: This medication is given by injection into a vein as directed by your doctor. Monitor Closely (1)iron sucrose decreases levels of methyldopa by inhibition of GI absorption. Most studies have used IV iron sucrose (maximum dose of 200 mg per setting) or ferric carboxymaltose (maximum dose of 1000 mg per week). Equations : Total body iron deficit (mg) = body weight (kg) x (target Hb - actual Hb in g/dL) x 2.4 + iron depot (mg)** [1, 2] Iron depot: 15 mg/kg for body weight less than 35 kg 500 mg for those with a body weight greater than or equal to 35 kg Ideal Body Weight (kg) =45.5 +2.3 * (height inches - 60 inches) [3] Applies only to oral form of both agents. Applies only to oral form of both agents. Minor/Significance Unknown. Applies only to oral form of both agents. pantoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Here are the steps to follow for using this drug dosage calculator: First, enter the value of your Weight and choose the unit of measurement from the drop-down menu. Reference www.medicines.org.uk Background Intravenous (IV) iron products (use in adults) Dosing information in this table is for adults and includes some dosing recommendations not listed in the approved product information. Consult your doctor for more details.Remember that it is best to get your vitamins and minerals from food whenever possible. Venofer must only be administered intravenously either by slow injection or by infusion. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=abacb7fa-2fc2-471e-9200-944eeac8ca2a. Serious - Use Alternative (1)iron sucrose decreases levels of ciprofloxacin by inhibition of GI absorption. Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Diagnosis and management of iron deficiency anaemia: a clinical update. Applies only to oral form of both agents. Schweiz Med Wochenschr; 100(7):301-3. When to Use Weight lbs Target hemoglobin g/dL Actual hemoglobin g/dL Iron stores Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg mg Result: Please fill out required fields. Other indications for IV are pregnancy iron deficiency, chronic renal impairment or need for rapid repletion. Applies only to oral form of both agents. Applies only to oral form of both agents. Each mL contains 20 mg of elemental . Use Caution/Monitor.Minor (2)calcium carbonate decreases levels of iron sucrose by inhibition of GI absorption. The recommendation is that most adults need a cumulative dose of elemental iron of at least 1 g. Iron replenishment can be done intravenously, either as total dose (example: iron-dextran or iron carboxymaltose) or as split dose (example: iron sucrose). iron sucrose, benazepril. Serious - Use Alternative (1)iron sucrose decreases levels of doxycycline by inhibition of GI absorption. Use Caution/Monitor. For repletion treatment most patients may require a cumulative dose of 1000 mg of elemental iron administered over 8 dialysis sessions. Hanson DB, Hendeles L. Guide to total dose intravenous iron dextran therapy. Monitor Closely (1)rabeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. iron sucrose decreases levels of moxifloxacin by inhibition of GI absorption. The dosing for iron replacement treatment in pediatric patients with HDD-CKD has not been established. Minor/Significance Unknown. There is limited experience with administration of an infusion of 500 mg of Venofer, diluted in a maximum of 250 mL of 0.9% NaCl, over a period of 3.5 to 4 hours on Day 1 and Day 14 [see How Supplied/Storage and Handling (16.2). No additional iron to replenish stores. Use Caution/Monitor. Untreated IDA in pregnancy is associated with adverse maternal outcomes such as post-partum anemia. Pediatric Patients (2 Years of Age and Older). ADMINISTER THE TEST DOSE AT A GRADUAL RATE OVER AT LEAST 30 SECONDS. The dosage of Venofer is expressed in mg of elemental iron. Applies only to oral form of both agents. Use Caution/Monitor. This website also contains material copyrighted by 3rd parties. Canada residents can call a provincial poison control center. Use Caution/Monitor. Allow at least 30 minutes between administration of Feraheme and administration of other medications that could potentially cause serious hypersensitivity reactions and/or hypotension, such as chemotherapeutic agents or monoclonal antibodies. Adult Patients with Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD): Administer Venofer 200 mg undiluted as a slow intravenous injection over 2 to 5 minutes or as an infusion of 200 mg in a maximum of 100 mL of 0.9% NaCl x 15 minutes. Congenital Pulmonary Airway Malformation Volume Ratio (CVR) Calculator -. J Lab Clin Med; 111(5):566-70. Studies in monkeys showed concurrent use with calcium, aluminum, or iron caused significantly decreased plasma levels. Minor/Significance Unknown. Fatal reactions have also occurred in situations where the test dose was tolerated. VenAccess is a trademark of Vifor (International) Inc. Switzerland. Monitor Closely (1)trientine, iron sucrose. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. To provide clinicians with evidence-based guidance for iron therapy dosing in patients with iron deficiency anemia (IDA), we conducted a study examining the benefits of a higher cumulative dose of intravenous (IV) iron than what is typically administered. Applies only to oral form of both agents. The Ganzoni equation used by the iron deficiency calculator is the following: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores. Transferrin saturation (TSAT) values increase rapidly after intravenous administration of iron sucrose; do not perform serum iron measurements for at least 48 hours after intravenous dosing. Venofer has not been studied in patients younger than 2 years old. Applies only to oral form of both agents. If you have private insurance, Venofer or Monoferric may be on the list of covered medications. Applies only to oral form of both agents. Iron Sucrose [ Venofer ] Elemental iron: 20 mg/mL (2.5 mL, 5 mL, 10 mL) Solution, Intravenous [preservative free]: [package insert] INDICATIONS: Venofer is an iron replacement product indicated for the treatment of iron deficiency anemia in patients with chronic kidney disease (CKD). Intravenous therapy is preferred for urgent intervention and when oral iron cannot be absorbed or the patient suffers from chronic renal impairment. Copyright 1993-2021 Use Caution/Monitor. 3. For iron maintenance treatment, administer Venofer, (2 years of age or older) with NDD-CKD or PDD-CKD who are on erythropoietin therapy for iron maintenance treatment. Modify Therapy/Monitor Closely. Applies only to oral form of both agents. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Venofer treatment may be repeated if iron deficiency reoccurs. Serious - Use Alternative (1)iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Applies only to oral form of both agents. Objective. If these effects continue or worsen, tell your doctor.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Avoid or Use Alternate Drug. WARNING: RISK FOR SERIOUS HYPERSENSITIVITY/ANAPHYLAXIS REACTIONS Fatal and serious hypersensitivity reactions including anaphylaxis have occurred in patients receiving Feraheme. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvdmVub2Zlci1pcm9uLXN1Y3Jvc2UtMzQyMTYy, View explanations for tiers and For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. Monitor Closely (1)iron sucrose decreases levels of deferiprone by enhancing GI absorption. )If you are using this medication at home, learn all preparation and usage instructions from your health care professional. iron sucrose decreases levels of ciprofloxacin by inhibition of GI absorption. Methods. Separate dosing of tetracyclines from these products. Feraheme, when added to intravenous infusion bags containing either 0.9% Sodium Chloride Injection, USP (normal saline), or 5% Dextrose Injection, USP, at concentrations of 2-8 mg elemental iron per mL, should be used immediately but may be stored at controlled room temperature (25C 2C) for up to 4 hours or refrigerated (2-8 C) for up to 48 hours. For patients receiving hemodialysis, administer Feraheme once the blood pressure is stable and the patient has completed at least one hour of hemodialysis. 2000 Jan;22(1):39-43. Med J Aust; 193(9):525-32. Iron metabolism needs to be balanced and bleeding, the major cause of iron deficiency (for instance in menstruation in females and chronic occult gastrointestinal bleeding) needs to be addressed. ONE DOSE. Monitor for signs and symptoms of hypotension following each administration of Venofer. Interaction only with oral iron administration. Either decreases levels of the other by inhibition of GI absorption. Individual doses of 2 mL or less may be given on a daily basis until the calculated total amount required has been reached. Where C= concentration of elemental iron (mg/ml) in the product being used: Data from Ferrlecit postmarketing spontaneous reports indicate that individual doses exceeding 125 mg may be associated with a higher incidence and/or severity of adverse events, Adult Patients with Hemodialysis Dependent-Chronic Kidney Disease (HDD-CKD), Adult Patients with Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD), WARNING: RISK FOR SERIOUS HYPERSENSITIVITY/ANAPHYLAXIS REACTIONS, Iron Deficiency and Anemia- signs and therapeutic options. Use Caution/Monitor. View the formulary and any restrictions for each plan. Always ask your health care professional for complete information about this product and your specific health needs. Consult your pharmacist or local waste disposal company. Inspect parenteral drug products visually for the absence of particulate matter and discoloration prior to administration. iron sucrose, captopril. Use Caution/Monitor. Most sodium sulfate/potassium sulfate/magnesium sulfate decreases levels of iron sucrose by inhibition of GI absorption. Deferasirox chelates iron. Minor/Significance Unknown.iron sucrose increases levels of calcium gluconate by enhancing GI absorption. David McAuley, Pharm.D. Monitor Closely (1)calcium carbonate will decrease the level or effect of iron sucrose by increasing gastric pH. NOTES: Lab and/or medical tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be done while you are using this medication. commonly, these are "preferred" (on formulary) brand drugs. Use Caution/Monitor. Deferoxamine chelates iron. Corrected Sodium and Effective Osmolality. iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. These adverse reactions have occurred up to 30 minutes after the administration of Venofer injection. This health tool computes the required parenteral iron replacement dose for the iron deficit extracted from the patient weight and hemoglobin level from complete blood count test. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. INFeD is given undiluted at a slow gradual rate not to exceed 50 mg (1 mL) per minute. Minor/Significance Unknown. Use Caution/Monitor. Interaction only with oral iron administration. trientine, iron sucrose. 2010; 193(9):525-32. 3) Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. (1988) Clinical use of the total dose intravenous infusion of iron dextran. Minor/Significance Unknown.iron sucrose increases levels of calcium citrate by enhancing GI absorption. 1) Ganzoni AM. May increase risk of hypotension. (2010) Diagnosis and management of iron deficiency anaemia: a clinical update. Burns DL, Mascioli EA, Bistrian BR. Formula for calculating the required dose of iron sucrose 1. Steps on how to print your input & results: 1. Calcs that help predict probability of a disease, Subcategory of 'Diagnosis' designed to be very sensitive, Disease is diagnosed: prognosticate to guide treatment. esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Minor/Significance Unknown.iron sucrose increases levels of calcium acetate by enhancing GI absorption. Minor/Significance Unknown. Applies only to oral form of both agents. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: vitamin products, other iron-containing products. vitamin E decreases levels of iron sucrose by increasing hepatic clearance. ANNA J. Applies only to oral form of both agents. It is unlikely . Use Caution/Monitor. Estimates the iron deficit in preparation for iron replacement based on patient weight and haemoglobin. Applies only to oral form of both agents. Administer Venofer early during the dialysis session (generally within the first hour). Serious - Use Alternative (1)iron sucrose decreases levels of fleroxacin by inhibition of GI absorption. Prescribing and dispensing information For iron sucrose A complex of ferric hydroxide with sucrose containing 2% (20 mg/mL) of iron. INDICATIONS AND USAGE: Intravenous or intramuscular injections of INFeD are indicated for treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. Serum iron, total iron binding capacity (TIBC) and percent saturation of transferrin are other important tests for detecting and monitoring the iron deficient state. When iron sucrose was administered at deliberate overdoses to rabbit dams (up to 215 mg/kg/day) marked fetal/placental iron overload was noted. Patients may present with shock, clinically significant hypotension, loss of consciousness and/or collapse. Drug class: Iron products. Monitor Closely (1)sodium citrate/citric acid will decrease the level or effect of iron sucrose by increasing gastric pH. The dosage of Venofer is expressed in mg of elemental iron. Applies only to oral form of both agents. Sodium ferric gluconate complex injection [ Ferrlecit ] [package insert] - Elemental iron: 12.5 mg/mL (5 mL). The factor 2.4 comes about from the calculation that the total iron content of hemoglobin is 0.34%, the blood volume accounts for 7% . Kumpf VJ. Calculosaurus | Medical calculators for obstetrics and gynaecology Use the menu to browse through our clinical calculators. Corrected Calcium. If either is present, do not use the liquid. iron sucrose increases levels of calcium acetate by enhancing GI absorption. Serious - Use Alternative (1)iron sucrose decreases levels of tetracycline by inhibition of GI absorption. The dose of Venofer must be individually calculated for each patient according to the total iron deficit calculated with the following Ganzoni formula, for example: Total iron deficit [mg] = BW [kg] x (target Hb - actual Hb) [g/dl] x 2.4* + storage iron [mg] Below 35 kg BW: 35 kg BW and above: Target Hb = 13 g/dl and storage iron = 15 mg/kg BW Use Caution/Monitor. Applies only to oral form of both agents. Venofer must only be administered intravenously either by slow injection or by infusion. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every two weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. Applies only to oral form of both agents. Applies only to oral form of both agents. Can't find what you need? Deferiprone may bind polyvalent cations (eg, iron, aluminum, and zinc), separate administration by at least 4 hr between deferiprone and other medications (eg, antacids), or supplements containing these polyvalent cations. Nutrition. Suggested regime: Prescribing instructions Prescribing a single/first dose: Avoid or Use Alternate Drug. Fill in the calculator/tool with your values and/or your answer choices and press Calculate. MDCalc loves calculator creators researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. Give each dose as 750 mg for a total cumulative dose not to exceed 1500 mg of iron per course. The original formula employs the weight in kg but users can input it in lbs and it gets transformed. 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